Spray Drying & Particle Engineering

Spray Drying and Particle Engineering in Oral Drug Development

Nanopharm offers advanced spray drying and particle engineering services to refine drug powders for optimal performance. Our expertise ensures control over particle size, morphology, and solubility, essential for developing effective oral inhaled and nasal drug products (OINDPs).

Particle Engineering

Particle size, morphology, and uniformity are key quality attributes of OINDPs, making particle engineering an essential technology for the design and manufacture of inhaled or nasal therapies. Nanopharm accelerates this complex process, both in terms of evaluating relevant approaches and employing appropriate manufacturing techniques.

Spray Drying

A proven technology for particle engineering and manufacturing dry powders with precise control over particle morphology and physical characteristics, spray drying is particularly beneficial for challenging APIs that require enhanced processability e.g. for higher drug loading, lower solubility compounds, and poor stability of the APIs. However, developing spray dried powders suitable for nasal or pulmonary administration requires an additional level of expertise to ensure aerosolization and dissolution at the site of action, as well as drug stability.

At Nanopharm, our suite of services includes spray drying and particle engineering as part of the product development process, which can later be transferred to our cGMP facility at our sister site, Aptar Boonton, for manufacture of clinical supplies.

Combining technical expertise, decades of scientific knowledge, and practical experience, our services play a crucial role in designing dry powder formulations with the optimal physical properties to achieve desired characteristics such as solubility and permeability, specifically for OINDPs.

Nanopharm OINDP Product Development Solutions

Nanopharm’s comprehensive OINDP development services can advance your nasal or inhaled product development process with scientific expertise, analytical technology, and state of the art development facilities, all in one company. Our collaborative support and specialized knowledge applied at any stage of development means you can accelerate your inhaled or nasal product while minimizing your risk.